Transit of pharmaceutical dosage forms through the small intestine.

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Transit of pharmaceutical dosage forms through the small intestine.

The gastrointestinal transit of pharmaceutical dosage forms has been measured in 201 studies in normal subjects using gamma scintigraphy. Solutions, small pellets, and single units (matrix tablets and osmotic pumps) were administered with different amounts of food in the stomach, ranging from fasted state to heavy breakfast. Gastric emptying was affected by the nature of the dosage form and the...

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ژورنال

عنوان ژورنال: Gut

سال: 1986

ISSN: 0017-5749

DOI: 10.1136/gut.27.8.886